ea0077op3.4 | Reproductive and Neuroendocrinology | SFEBES2021
Willis Thea L.
, Yianni Val
, Santambrogio Alice
, Russell John P
, Lodge Emily
, Charalambous Marika
, Andoniadou Cynthia L.
The anterior pituitary gland is a critical endocrine organ responsible for many important physiological processes including puberty, fertility, metabolism and the stress response. It is derived from, and maintained by, a population of SOX2+ progenitor/stem cells which become more quiescent with age until their direct contribution to tissue turnover becomes negligible. Previous research has demonstrated that the postnatal SOX2+ population exhibits heterogeneity in terms of mark...